Discovered the hidden cause of increased blood pressure

The reason for the increased pressure may be the work of the area of the brain, which was previously associated mainly with respiratory control. The researchers found that its excessive activity can enhance signals of the nervous system, leading to narrowing of blood vessels. The work was published in the scientific journal Circulation Research.

In the center of attention of scientists was the lateral parafacial region (pFL). It is involved in the regulation of breathing during exercise, coughing and other conditions. Experiments on rats have shown that in hypertension, neurons in this zone can further affect the cardiovascular system.

With the artificial activation of pFL cells in animals, the activity of the sympathetic nervous system increased, the vessels narrowed, and blood pressure increased. Suppression of the work of this site in rats with hypertension, on the contrary, led to pressure to normal parameters.

The discovery could also help explain the link between hypertension and sleep apnea. Changes in oxygen and carbon dioxide levels during respiratory arrests can trigger the mechanism. Now the researchers intend to find out whether it can be affected without direct intervention in the brain.

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