Cats may help treat cancer in humans

An international team of scientists conducted the largest genetic study of cancer of domestic cats. Researchers analyzed tumours from nearly 500 animals in five countries and found numerous genetic features that are also found in human and dog cancers. The results are published in the journal Science.

Particular attention of researchers attracted aggressive breast tumors. More than half of the samples studied showed a mutation in the FBXW7 gene involved in controlling cell growth and division. Disorders in the work of the same gene are known in some types of human cancer.

Similar genetic changes were found in tumors of the blood, lungs, bones, skin, digestive organs and the central nervous system. Researchers admit that environmental factors common to people and pets — air pollution, smoke and exposure to various household substances — may play a role.

The findings could help veterinarians better select anti-tumor therapy for animals. At the same time, the study of naturally occurring cancer in cats in the future can provide new information about the mechanisms of development of cancer in humans.

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